5'3' Frame 1 idseqsvlineartnassigneddnastdtncbpxxdebpxxxxsqseqtencebpacgt X X X X X X X X X X X X X X X X X X X R otheratgcttttttgtgctattatgatgatttgttgtgttcttgttatgatttgttttt X X C F F V L L - - F V V F L L - F V F ttattattattcttgctctttgtctttttgtttgttgtgctattattgtttttattatga L L L F L L F V F L F V V L L L F L L - ttatgatttgttgtcttcttctttgttttattattcttctttttttttttcttattattc L - F V V F F F V L L F F F F F F L L F ttgctctttgtctttttgttctttttttttttcttgtttttattatgatttgttttattt L L F V F L F F F F F L F L L - F V L F gtcttattatgtgttttcttgttcttgctgttattatttttatgatttttgctcttatgt V L L C V F L F L L L L F L - F L L L C ttgttatggctattcttattattcttatgatggctctttttattcttgcttgtgctctta L L W L F L L F L - W L F L F L L V L L ttgttcttgctgttttttttcttgttatttttatgatttttgctcttxttatgatgcttg L F L L F F F L L F L - F L L X L - C L tttttatttttatgatttttgctcttatgcttgctgctctttttattctttttgttatta F L F L - F L L L C L L L F L F F L L L tggctattcttattattctttttatgattatgatttttatgatttttgctctttgtcttg W L F L L F F L - L - F L - F L L F V L ctatttgttttattatgtttgttgttgttattattattatgcttcttatgtttgttgttt L F V L L C L L L L L L L C F L C L L F ttattgttgctgtttttcttatgattatggttgctgtttgtgttatggttgctcttcttg L L L L F F L - L W L L F V L W L L F L ttgttattattattatgcttcttatgattatggttgctgtttgtgttatggttgctcttc L L L L L C F L - L W L L F V L W L L F ttgttgttattattattatgcttcttgtttttattcttttttttattatgatggttgctc L L L L L L C F L F L F F F L L - W L L ttcttatgcttgttgttattattatggttatttgtattattgtttgtctttgtctttgtg F L C L L L L L W L F V L L F V F V F V ttttttttgtttttcttatgattatgtgttgtcttcttcttattcttgctcttatgattc F F L F F L - L C V V F F L F L L L - F ttgctctttgttttattattcttcttctttttgctcttattattgttcttattgttgtta L L F V L L F F F F L L L L L F L L L L ttatttgttttgctcttctttttttttgtcttcttcttctttgtattgttcttatgatta L F V L L F F F F V F F F F V L F L - L tgattattcttattatgatttgttttatgtgttgttgtattatttttcttattgttctta - L F L L - F V L C V V V L F F L L F L ttatggttattcttattattatgcttctttgtattgtttttcttatgtttgttgtttttc L W L F L L L C F F V L F F L C L L F F ttatgtttgttattgtttttgttgttattatgcttcttattattcttatgatgattattg L C L L L F L L L L C F L L F L - - L L ttattatgcttctttgtatttttgtttttctttgtgttattcttgctcttattattctta L L C F F V F L F F F V L F L L L L F L tggcttgtattatggctcttctttttgctcttattgttgctattatttgtcttatggcta W L V L W L F F L L L L L L L F V L W L ttctttttgtttttattcttatttttctttgtatttttgttattgtttttattttttttg F F L F L F L F F F V F L L L F L F F L ttcttgctcttattatgtttgtttgtattgcttgtgctattattatgattgttgctatgt F L L L L C L F V L L V L L L - L L L C gttgtcttattattattgttatgattattatgtgttttcttattatttgtcttgctgttg V V L L L L L - L L C V F L L F V L L L ctattgttcttattatgatggctattcttattatgtgttgttttcttcttcttgctcttt L L F L L - W L F L L C V V F F F L L F ttgttatgatggctattcttcttgctgttgcttttctttttgttgcttttatgatttttg L L - W L F F L L L L F F L L L L - F L ctcttcttatttgtgctattatttttgttgctattcttattattatgcttcttatggtta L F L F V L L F L L L F L L L C F L W L tgcttgctgttgctgtttttcttatgtttgttgtttttcttcttgttatttgttgtatta C L L L L F F L C L L F F F L L F V V L ttgttattatgcttcttgttattgtttttcttgcttgttgtattgtttttcttttttttg L L L C F L L L F F L L V V L F F F F L cttgttgttgtgttgcttgttgtatt L V V V L L V V 5'3' Frame 2 idseqsvlineartnassigneddnastdtncbpxxdebpxxxxsqseqtencebpacgto X X X X X X X X X X X X X X X X X X X X theratgcttttttgtgctattatgatgatttgttgtgttcttgttatgatttgtttttt X X A F L C Y Y D D L L C S C Y D L F F tattattattcttgctctttgtctttttgtttgttgtgctattattgtttttattatgat Y Y Y S C S L S F C L L C Y Y C F Y Y D tatgatttgttgtcttcttctttgttttattattcttctttttttttttcttattattct Y D L L S S S L F Y Y S S F F F S Y Y S tgctctttgtctttttgttctttttttttttcttgtttttattatgatttgttttatttg C S L S F C S F F F S C F Y Y D L F Y L tcttattatgtgttttcttgttcttgctgttattatttttatgatttttgctcttatgtt S Y Y V F S C S C C Y Y F Y D F C S Y V tgttatggctattcttattattcttatgatggctctttttattcttgcttgtgctcttat C Y G Y S Y Y S Y D G S F Y S C L C S Y tgttcttgctgttttttttcttgttatttttatgatttttgctcttxttatgatgcttgt C S C C F F S C Y F Y D F C S X Y D A C ttttatttttatgatttttgctcttatgcttgctgctctttttattctttttgttattat F Y F Y D F C S Y A C C S F Y S F C Y Y ggctattcttattattctttttatgattatgatttttatgatttttgctctttgtcttgc G Y S Y Y S F Y D Y D F Y D F C S L S C tatttgttttattatgtttgttgttgttattattattatgcttcttatgtttgttgtttt Y L F Y Y V C C C Y Y Y Y A S Y V C C F tattgttgctgtttttcttatgattatggttgctgtttgtgttatggttgctcttcttgt Y C C C F S Y D Y G C C L C Y G C S S C tgttattattattatgcttcttatgattatggttgctgtttgtgttatggttgctcttct C Y Y Y Y A S Y D Y G C C L C Y G C S S tgttgttattattattatgcttcttgtttttattcttttttttattatgatggttgctct C C Y Y Y Y A S C F Y S F F Y Y D G C S tcttatgcttgttgttattattatggttatttgtattattgtttgtctttgtctttgtgt S Y A C C Y Y Y G Y L Y Y C L S L S L C tttttttgtttttcttatgattatgtgttgtcttcttcttattcttgctcttatgattct F F C F S Y D Y V L S S S Y S C S Y D S tgctctttgttttattattcttcttctttttgctcttattattgttcttattgttgttat C S L F Y Y S S S F C S Y Y C S Y C C Y tatttgttttgctcttctttttttttgtcttcttcttctttgtattgttcttatgattat Y L F C S S F F L S S S S L Y C S Y D Y gattattcttattatgatttgttttatgtgttgttgtattatttttcttattgttcttat D Y S Y Y D L F Y V L L Y Y F S Y C S Y tatggttattcttattattatgcttctttgtattgtttttcttatgtttgttgtttttct Y G Y S Y Y Y A S L Y C F S Y V C C F S tatgtttgttattgtttttgttgttattatgcttcttattattcttatgatgattattgt Y V C Y C F C C Y Y A S Y Y S Y D D Y C tattatgcttctttgtatttttgtttttctttgtgttattcttgctcttattattcttat Y Y A S L Y F C F S L C Y S C S Y Y S Y ggcttgtattatggctcttctttttgctcttattgttgctattatttgtcttatggctat G L Y Y G S S F C S Y C C Y Y L S Y G Y tctttttgtttttattcttatttttctttgtatttttgttattgtttttattttttttgt S F C F Y S Y F S L Y F C Y C F Y F F C tcttgctcttattatgtttgtttgtattgcttgtgctattattatgattgttgctatgtg S C S Y Y V C L Y C L C Y Y Y D C C Y V ttgtcttattattattgttatgattattatgtgttttcttattatttgtcttgctgttgc L S Y Y Y C Y D Y Y V F S Y Y L S C C C tattgttcttattatgatggctattcttattatgtgttgttttcttcttcttgctctttt Y C S Y Y D G Y S Y Y V L F S S S C S F tgttatgatggctattcttcttgctgttgcttttctttttgttgcttttatgatttttgc C Y D G Y S S C C C F S F C C F Y D F C tcttcttatttgtgctattatttttgttgctattcttattattatgcttcttatggttat S S Y L C Y Y F C C Y S Y Y Y A S Y G Y gcttgctgttgctgtttttcttatgtttgttgtttttcttcttgttatttgttgtattat A C C C C F S Y V C C F S S C Y L L Y Y tgttattatgcttcttgttattgtttttcttgcttgttgtattgtttttcttttttttgc C Y Y A S C Y C F S C L L Y C F S F F C ttgttgttgtgttgcttgttgtatt L L L C C L L Y 5'3' Frame 3 idseqsvlineartnassigneddnastdtncbpxxdebpxxxxsqseqtencebpacgtot X X X X X X X X X X X X X X X X X X T X heratgcttttttgtgctattatgatgatttgttgtgttcttgttatgatttgttttttt X M L F C A I M M I C C V L V M I C F F attattattcttgctctttgtctttttgtttgttgtgctattattgtttttattatgatt I I I L A L C L F V C C A I I V F I M I atgatttgttgtcttcttctttgttttattattcttctttttttttttcttattattctt M I C C L L L C F I I L L F F F L I I L gctctttgtctttttgttctttttttttttcttgtttttattatgatttgttttatttgt A L C L F V L F F F L V F I M I C F I C cttattatgtgttttcttgttcttgctgttattatttttatgatttttgctcttatgttt L I M C F L V L A V I I F M I F A L M F gttatggctattcttattattcttatgatggctctttttattcttgcttgtgctcttatt V M A I L I I L M M A L F I L A C A L I gttcttgctgttttttttcttgttatttttatgatttttgctcttxttatgatgcttgtt V L A V F F L V I F M I F A L X M M L V tttatttttatgatttttgctcttatgcttgctgctctttttattctttttgttattatg F I F M I F A L M L A A L F I L F V I M gctattcttattattctttttatgattatgatttttatgatttttgctctttgtcttgct A I L I I L F M I M I F M I F A L C L A atttgttttattatgtttgttgttgttattattattatgcttcttatgtttgttgttttt I C F I M F V V V I I I M L L M F V V F attgttgctgtttttcttatgattatggttgctgtttgtgttatggttgctcttcttgtt I V A V F L M I M V A V C V M V A L L V gttattattattatgcttcttatgattatggttgctgtttgtgttatggttgctcttctt V I I I M L L M I M V A V C V M V A L L gttgttattattattatgcttcttgtttttattcttttttttattatgatggttgctctt V V I I I M L L V F I L F F I M M V A L cttatgcttgttgttattattatggttatttgtattattgtttgtctttgtctttgtgtt L M L V V I I M V I C I I V C L C L C V ttttttgtttttcttatgattatgtgttgtcttcttcttattcttgctcttatgattctt F F V F L M I M C C L L L I L A L M I L gctctttgttttattattcttcttctttttgctcttattattgttcttattgttgttatt A L C F I I L L L F A L I I V L I V V I atttgttttgctcttctttttttttgtcttcttcttctttgtattgttcttatgattatg I C F A L L F F C L L L L C I V L M I M attattcttattatgatttgttttatgtgttgttgtattatttttcttattgttcttatt I I L I M I C F M C C C I I F L I V L I atggttattcttattattatgcttctttgtattgtttttcttatgtttgttgtttttctt M V I L I I M L L C I V F L M F V V F L atgtttgttattgtttttgttgttattatgcttcttattattcttatgatgattattgtt M F V I V F V V I M L L I I L M M I I V attatgcttctttgtatttttgtttttctttgtgttattcttgctcttattattcttatg I M L L C I F V F L C V I L A L I I L M gcttgtattatggctcttctttttgctcttattgttgctattatttgtcttatggctatt A C I M A L L F A L I V A I I C L M A I ctttttgtttttattcttatttttctttgtatttttgttattgtttttattttttttgtt L F V F I L I F L C I F V I V F I F F V cttgctcttattatgtttgtttgtattgcttgtgctattattatgattgttgctatgtgt L A L I M F V C I A C A I I M I V A M C tgtcttattattattgttatgattattatgtgttttcttattatttgtcttgctgttgct C L I I I V M I I M C F L I I C L A V A attgttcttattatgatggctattcttattatgtgttgttttcttcttcttgctcttttt I V L I M M A I L I M C C F L L L A L F gttatgatggctattcttcttgctgttgcttttctttttgttgcttttatgatttttgct V M M A I L L A V A F L F V A F M I F A cttcttatttgtgctattatttttgttgctattcttattattatgcttcttatggttatg L L I C A I I F V A I L I I M L L M V M cttgctgttgctgtttttcttatgtttgttgtttttcttcttgttatttgttgtattatt L A V A V F L M F V V F L L V I C C I I gttattatgcttcttgttattgtttttcttgcttgttgtattgtttttcttttttttgct V I M L L V I V F L A C C I V F L F F A tgttgttgtgttgcttgttgtatt C C C V A C C I 3'5' Frame 1 aatacaacaagcaacacaacaacaagcaaaaaaaagaaaaacaatacaacaagcaagaaa N T T S N T T T S K K K K N N T T S K K aacaataacaagaagcataataacaataatacaacaaataacaagaagaaaaacaacaaa N N N K K H N N N N T T N N K K K N N K cataagaaaaacagcaacagcaagcataaccataagaagcataataataagaatagcaac H K K N S N S K H N H K K H N N K N S N aaaaataatagcacaaataagaagagcaaaaatcataaaagcaacaaaaagaaaagcaac K N N S T N K K S K N H K S N K K K S N agcaagaagaatagccatcataacaaaaagagcaagaagaagaaaacaacacataataag S K K N S H H N K K S K K K K T T H N K aatagccatcataataagaacaatagcaacagcaagacaaataataagaaaacacataat N S H H N K N N S N S K T N N K K T H N aatcataacaataataataagacaacacatagcaacaatcataataatagcacaagcaat N H N N N N K T T H S N N H N N S T S N acaaacaaacataataagagcaagaacaaaaaaaataaaaacaataacaaaaatacaaag T N K H N K S K N K K N K N N N K N T K aaaaataagaataaaaacaaaaagaatagccataagacaaataatagcaacaataagagc K N K N K N K K N S H K T N N S N N K S aaaaagaagagccataatacaagccataagaataataagagcaagaataacacaaagaaa K K K S H N T S H K N N K S K N N T K K aacaaaaatacaaagaagcataataacaataatcatcataagaataataagaagcataat N K N T K K H N N N N H H K N N K K H N aacaacaaaaacaataacaaacataagaaaaacaacaaacataagaaaaacaatacaaag N N K N N N K H K K N N K H K K N N T K aagcataataataagaataaccataataagaacaataagaaaaataatacaacaacacat K H N N K N N H N K N N K K N N T T T H aaaacaaatcataataagaataatcataatcataagaacaatacaaagaagaagaagaca K T N H N K N N H N H K N N T K K K K T aaaaaaaagaagagcaaaacaaataataacaacaataagaacaataataagagcaaaaag K K K K S K T N N N N N K N N N K S K K aagaagaataataaaacaaagagcaagaatcataagagcaagaataagaagaagacaaca K K N N K T K S K N H K S K N K K K T T cataatcataagaaaaacaaaaaaaacacaaagacaaagacaaacaataatacaaataac H N H K K N K K N T K T K T N N N T N N cataataataacaacaagcataagaagagcaaccatcataataaaaaaaagaataaaaac H N N N N K H K K S N H H N K K K N K N aagaagcataataataataacaacaagaagagcaaccataacacaaacagcaaccataat K K H N N N N N K K S N H N T N S N H N cataagaagcataataataataacaacaagaagagcaaccataacacaaacagcaaccat H K K H N N N N N K K S N H N T N S N H aatcataagaaaaacagcaacaataaaaacaacaaacataagaagcataataataataac N H K K N S N N K N N K H K K H N N N N aacaacaaacataataaaacaaatagcaagacaaagagcaaaaatcataaaaatcataat N N K H N K T N S K T K S K N H K N H N cataaaaagaataataagaatagccataataacaaaaagaataaaaagagcagcaagcat H K K N N K N S H N N K K N K K S S K H aagagcaaaaatcataaaaataaaaacaagcatcataaxaagagcaaaaatcataaaaat K S K N H K N K N K H H X K S K N H K N aacaagaaaaaaaacagcaagaacaataagagcacaagcaagaataaaaagagccatcat N K K K N S K N N K S T S K N K K S H H aagaataataagaatagccataacaaacataagagcaaaaatcataaaaataataacagc K N N K N S H N K H K S K N H K N N N S aagaacaagaaaacacataataagacaaataaaacaaatcataataaaaacaagaaaaaa K N K K T H N K T N K T N H N K N K K K aaaaagaacaaaaagacaaagagcaagaataataagaaaaaaaaaaagaagaataataaa K K N K K T K S K N N K K K K K K N N K acaaagaagaagacaacaaatcataatcataataaaaacaataatagcacaacaaacaaa T K K K T T N H N H N K N N N S T T N K aagacaaagagcaagaataataataaaaaaacaaatcataacaagaacacaacaaatcat K T K S K N N N K K T N H N K N T T N H cataatagcacaaaaaagcatrehaoacgtpbegneaqesqsxxxxpbedxxpbgnadas H N S T K K H X X R X X X X X X X X X X tnddencasstnartenacvsqesda X X X X X X X X X 3'5' Frame 2 aatacaacaagcaacacaacaacaagcaaaaaaaagaaaaacaatacaacaagcaagaaaa I Q Q A T Q Q Q A K K R K T I Q Q A R K acaataacaagaagcataataacaataatacaacaaataacaagaagaaaaacaacaaac T I T R S I I T I I Q Q I T R R K T T N ataagaaaaacagcaacagcaagcataaccataagaagcataataataagaatagcaaca I R K T A T A S I T I R S I I I R I A T aaaataatagcacaaataagaagagcaaaaatcataaaagcaacaaaaagaaaagcaaca K I I A Q I R R A K I I K A T K R K A T gcaagaagaatagccatcataacaaaaagagcaagaagaagaaaacaacacataataaga A R R I A I I T K R A R R R K Q H I I R atagccatcataataagaacaatagcaacagcaagacaaataataagaaaacacataata I A I I I R T I A T A R Q I I R K H I I atcataacaataataataagacaacacatagcaacaatcataataatagcacaagcaata I I T I I I R Q H I A T I I I I A Q A I caaacaaacataataagagcaagaacaaaaaaaataaaaacaataacaaaaatacaaaga Q T N I I R A R T K K I K T I T K I Q R aaaataagaataaaaacaaaaagaatagccataagacaaataatagcaacaataagagca K I R I K T K R I A I R Q I I A T I R A aaaagaagagccataatacaagccataagaataataagagcaagaataacacaaagaaaa K R R A I I Q A I R I I R A R I T Q R K acaaaaatacaaagaagcataataacaataatcatcataagaataataagaagcataata T K I Q R S I I T I I I I R I I R S I I acaacaaaaacaataacaaacataagaaaaacaacaaacataagaaaaacaatacaaaga T T K T I T N I R K T T N I R K T I Q R agcataataataagaataaccataataagaacaataagaaaaataatacaacaacacata S I I I R I T I I R T I R K I I Q Q H I aaacaaatcataataagaataatcataatcataagaacaatacaaagaagaagaagacaa K Q I I I R I I I I I R T I Q R R R R Q aaaaaaagaagagcaaaacaaataataacaacaataagaacaataataagagcaaaaaga K K R R A K Q I I T T I R T I I R A K R agaagaataataaaacaaagagcaagaatcataagagcaagaataagaagaagacaacac R R I I K Q R A R I I R A R I R R R Q H ataatcataagaaaaacaaaaaaaacacaaagacaaagacaaacaataatacaaataacc I I I R K T K K T Q R Q R Q T I I Q I T ataataataacaacaagcataagaagagcaaccatcataataaaaaaaagaataaaaaca I I I T T S I R R A T I I I K K R I K T agaagcataataataataacaacaagaagagcaaccataacacaaacagcaaccataatc R S I I I I T T R R A T I T Q T A T I I ataagaagcataataataataacaacaagaagagcaaccataacacaaacagcaaccata I R S I I I I T T R R A T I T Q T A T I atcataagaaaaacagcaacaataaaaacaacaaacataagaagcataataataataaca I I R K T A T I K T T N I R S I I I I T acaacaaacataataaaacaaatagcaagacaaagagcaaaaatcataaaaatcataatc T T N I I K Q I A R Q R A K I I K I I I ataaaaagaataataagaatagccataataacaaaaagaataaaaagagcagcaagcata I K R I I R I A I I T K R I K R A A S I agagcaaaaatcataaaaataaaaacaagcatcataaxaagagcaaaaatcataaaaata R A K I I K I K T S I I X R A K I I K I acaagaaaaaaaacagcaagaacaataagagcacaagcaagaataaaaagagccatcata T R K K T A R T I R A Q A R I K R A I I agaataataagaatagccataacaaacataagagcaaaaatcataaaaataataacagca R I I R I A I T N I R A K I I K I I T A agaacaagaaaacacataataagacaaataaaacaaatcataataaaaacaagaaaaaaa R T R K H I I R Q I K Q I I I K T R K K aaaagaacaaaaagacaaagagcaagaataataagaaaaaaaaaaagaagaataataaaa K R T K R Q R A R I I R K K K R R I I K caaagaagaagacaacaaatcataatcataataaaaacaataatagcacaacaaacaaaa Q R R R Q Q I I I I I K T I I A Q Q T K agacaaagagcaagaataataataaaaaaacaaatcataacaagaacacaacaaatcatc R Q R A R I I I K K Q I I T R T Q Q I I ataatagcacaaaaaagcatrehaoacgtpbegneaqesqsxxxxpbedxxpbgnadast I I A Q K S X X X X X X X X X X X X X X nddencasstnartenacvsqesda X X X X X X X X 3'5' Frame 3 aatacaacaagcaacacaacaacaagcaaaaaaaagaaaaacaatacaacaagcaagaaaaa Y N K Q H N N K Q K K E K Q Y N K Q E K caataacaagaagcataataacaataatacaacaaataacaagaagaaaaacaacaaaca Q - Q E A - - Q - Y N K - Q E E K Q Q T taagaaaaacagcaacagcaagcataaccataagaagcataataataagaatagcaacaa - E K Q Q Q Q A - P - E A - - - E - Q Q aaataatagcacaaataagaagagcaaaaatcataaaagcaacaaaaagaaaagcaacag K - - H K - E E Q K S - K Q Q K E K Q Q caagaagaatagccatcataacaaaaagagcaagaagaagaaaacaacacataataagaa Q E E - P S - Q K E Q E E E N N T - - E tagccatcataataagaacaatagcaacagcaagacaaataataagaaaacacataataa - P S - - E Q - Q Q Q D K - - E N T - - tcataacaataataataagacaacacatagcaacaatcataataatagcacaagcaatac S - Q - - - D N T - Q Q S - - - H K Q Y aaacaaacataataagagcaagaacaaaaaaaataaaaacaataacaaaaatacaaagaa K Q T - - E Q E Q K K - K Q - Q K Y K E aaataagaataaaaacaaaaagaatagccataagacaaataatagcaacaataagagcaa K - E - K Q K E - P - D K - - Q Q - E Q 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